UMass Boston

澳门新葡新京官方的核心设施带来了尖端的仪器, 为我们的研究界提供方法和专业知识. These facilities not only provide high quality research services by our in-house experts but also constitute a major educational resource for our growing research enterprise. 作为按服务收费的设施运营，其中一些也可供外部研究人员使用.

澳门新葡新京官方核心设施创新券计划
A state voucher program funded by the Massachusetts legislature gives small and medium-sized businesses (<50 FTEs) access to the University’s leading-edge research facilities at reduced rates. 所有澳门新葡新京官方的核心设施都可以使用代金券计划.

Voucher Eligibility

• Companies with 50 or less FTEs, 总部设在麻萨诸塞州，并在麻萨诸塞州注册经商
• 初创企业和员工少于10人的公司可获得75%的补贴.
• 拥有11-50名员工的初创企业和公司可获得50%的补贴

UMass Core Facilities Benefits

• Highly competitive rates
• 由全职经验丰富的专业人士管理
• 分层访问设备和服务
• Streamlined contracts
• 先进的设施和设备

有关澳门新葡新京官方核心设施或代金券计划的信息，请联系: Serena.Wang@goudounet.com  

Genomics Core Facility

The Genomics Core service model fills a critical gap in genomics research by offering tailored services that move early ideas through feasibility assessment to project completion. 我们为探索提供了一个方便的场所, 高风险/潜在高回报的基因组学研究, 特别是那些需要创新和/或技术上具有挑战性的方法. 你有什么想法可以从单细胞细胞中获益吗, high-throughput, or re-sequencing approaches? 或者使用NanoString等新技术对基因表达水平进行二次验证? 给我们打电话或发邮件! We're here to help you.

Equipment

• Illumina NextSeq 2000
• Agilent 2100 Bioanalyzer
• Agilent 2200 Tapestation
• Qubit
• Nanodrop Lite
• 纳米串计数器分析系统
• Quantstudio 12K Flex实时PCR系统

Contact
Email: genomicscore@goudounet.com
Phone: 617-287-6578
PI: Jill Macoska
Website: http://0951w.goudounet.com/genomicscore

Vivarium Core Facility

The Animal Resources Core Facility and Vivarium is dedicated to providing the highest level of care possible to animals used in research and teaching. All aspects of animal research are reviewed by the UMass Boston Institutional Animal Care and Use Committee (IACUC) and is overseen by the Office of Research and Sponsored Programs.

The state-of-the-art vivarium in the Integrated Sciences Complex on the UMass Boston campus provides housing for specific pathogen free species including, rodents, frogs, reptiles, and zebra fish.  The vivarium consists of a total 7,515 square feet space with 2,744平方英尺的动物专用住房.  平面图为单走廊设计，有分支走廊通往笼子盥洗室, 各种程序和住房房间, behavioural test rooms, and suites. 

监测和环境控制
除了独立控制的房间隔间, 动物园内的气候由楼宇监测系统(BMS)控制和监测。. The vivarium lighting is programmable with multiple intensity settings to accommodate the workers and the animals. 单独通风的啮齿动物饲养系统(IVC)有标准的笼子和接触式床褥. Security is maintained through camera surveillance and a key-card entry system controlled by the BMS.

Contact
Contact Us

Facility Manager: Elizabeth Boates
Website: http://0951w.goudounet.com/arcf

Proteomics Core Facility

The UMass Boston Proteomics Core offers a full range of proteomic services using an Orbitrap Fusion Lumos Tribrid mass spectrometer at highly competitive rates. 我们的服务范围从样品制备, bottom-up protein identification, 使用无标签和TMT多路复用策略定量表达水平, PTM analysis, 2D fractionation, and top-down proteomic analysis. Our instrumentation offers unique flexibility in designing proteomic experiments to provide the best outcome for your project. The director of the core, Professor Jason Evans, 在质谱和蛋白质组学领域有超过25年的经验, and as a facility we have been servicing the proteomics needs of multiple principle investigators at the University of Massachusetts Boston since the Spring of 2016. 我们提供无与伦比的客户服务, taking the time to consult with you to learn your needs and formulate the best plan for analyzing your samples, 这样你就能最大限度地利用结果数据. 我们非常努力地工作，以使我们的周转时间尽可能短. In addition, 作为澳门新葡新京官方的核心设施, we are currently in a unique position to offer our services to small businesses with less than 10 employees at a 75% discount and to small businesses with less than 50 employees a 50% discount from subsidies provided though the state of Massachusetts.

Equipment
蛋白质组学核心目前使用的是最先进的技术 Orbitrap Fusion Lumos Tribird Easy-ETD升级后的质谱仪与任何一种 Easy-nLC 1200 or an UltiMate 3000RS HPLC. The core uses the Thermo Xcalibur 运行设备和分析原始数据文件的程序套件. 对于自下而上的研究，核心用途 Thermo Proteome Discoverer 鉴定和/或定量客户样品中表达的蛋白. 对于自顶向下的研究，核心使用 ProSightLite application.

Contact
Email: Proteomics.Core@goudounet.com 
Phone: 617-287-6149
PI:  Jason Evans
Website: http://0951w.goudounet.com/proteomicscore

成像核心配备了蔡司的共聚焦显微镜, a shared resource open to the UMass Community and member companies at the Venture Development Center on campus.

Contact
Email: Alexey.Veraksa@goudounet.com
PI:  Alexey Veraksa
Website: Veraksa Lab (goudounet.com)

环境分析堆芯设备

Offers state-of-the-art environmental instrumentation for chemical and material property analysis of environmental samples including natural waters, soils, sediments, and biological tissues. The facility includes two inductively coupled plasma mass spectrometers (a quadrupole instrument and a high resolution, magnetic sector instrument), isotope ratio mass spectrometer, GC mass spectrometer, and several peripherals (e.g.(激光烧蚀，高效液相色谱)用于固体和水形态的连合金属分析. A class 100 (ESO 5) clean room facility and several class 100 clean benches are part of the facility. The Core facility also includes Scanning (SEM) and Field Emission (FESEM) Scanning Electron Microscopes and technical expertise for the characterization of nano-engineered materials, microelectronics, and others.

Equipment

• 同位素比质谱仪(IRMS)
• 气相色谱-质谱仪(GC-MS)
• 电感耦合等离子体质谱计(ICP-MS)
• ICP-MS外围设备和处理设备
• Electron Microscopy
• Microscopy
• Elemental Analyzer (EA)
• 电感耦合等离子体发射光谱法(ICP-OES)
• 冷蒸汽原子荧光光谱(CVAFS)
• 傅里叶变换红外光谱(FTIR)
• Mercury Analyzers
• Sediment Digestion Systems
• Dissolved Inorganic/Organics
• UV-Vis Spectrometers
• Fluorometer
• Digital Microbalances
• ED-XRF

Contact
Email: EACF@goudounet.com
Phone: 617-287-5562
PI: Karen Johannesson
Website:  http://0951w.goudounet.com/eaf

生物物理仪器核心设施

The 生物物理仪器核心设施 is equipped with state-of-the-art instrumentation to aid researchers in characterizing molecular interactions, sample integrity, stability, structure, and more. Core对内部和外部用户开放.

• 荧光和荧光各向异性
• 圆二色(CD)和LD光谱
• Absorbance spectroscopy
• Binding affinity (KD)
• 动态光散射和多角度光散射
• 等温滴定量热法
• 差示扫描量热法(DSC)

The Quantum core facility offers access to quantum device characterization and fabrication facilities in Boston Massachusetts to the quantum information science and engineering industry for quantum device development and commercialization. Quantum device fabrication capabilities include a class 1000 cleanroom facility with electron beam and optical lithographic capabilities as well as metal deposition of superconducting metals with electron beam and sputter deposition processes. 封装和表征能力包括原子力显微镜, scanning electron microscopy, 4-point probe stations, and wire bonders. 低温测量系统包括两个无冷冻剂稀释冰箱, 氦-3低温恒温器和4k低温恒温器用于直流和射频测量. 一套测量电子设备，包括高频矢量网络分析仪, spectrum analysers, microwave synthesizers and DC sources are available for low temperature electrical characterization of quantum devices. Characterization of quantum devices at the Quantum Core can be done in a remote modality with network access available to measurement computers and electronics. 技术专长也可通过核心设施获得.

Contact
Email: Matthew.Bell@goudounet.com
PI:  Matthew Bell

扫描电子显微镜(FESEM)核心设备

ZEISS Sigma500VP FESEM is an advanced field emission SEM that produces exceptional images at high and low accelerating voltages. 以及它的分析能力, 这种仪器适用范围很广. 仪器配有高分辨率场发射柱和高稳定性肖特基场炮, 光束电流范围从1pa到400na, 加速电压范围为200ev ~ 30kev.

探测器:透镜内二次电子, 埃弗哈特-索恩利二次电子, 变压二次电子, backscattered electron. 

The instrument is equipped with Oxford energy dispersive spectroscopy (EDS) system for elemental and chemical analysis of a sample inside the SEM. 

Contact
Email: SEM@goudounet.com
PI: Niya Sa
Website:  http://saniyabnu.wixsite.com/niyasa

AI Core Facility

The Artificial Intelligence Core provides infrastructure and algorithms for machine learning on massive data collections. Services include specialized data management and targeted software development to minimize the cost of manual data processing.

Contact:
Email: daniel.haehn@goudounet.com
PI: Daniel Haehn
Website: http://mpsych.org/

Flow Cytometry Core Facility

The Flow Cytometry Core Facility enables UMass Boston investigators and academic and industry collaborators to carry out basic and translational cellular and molecular biology research.  我们利用尖端技术进行研究和临床应用.  我们帮助调查人员和临床医生分析组织样本, identify and quantify different populations of cells based on the presence of cell-specific fluorescent signatures, 并收集感兴趣的细胞群作进一步分析.